8 Best Drain Fly Killers That Actually Work In 2026

While a sewage system remains an effective way for managing household wastewater, there are some concerns that come along with it. And the most annoying one among them is the drain flies, also called moth flies or sewer flies.

A drain fly is a tiny insect that breeds in damp organic matter inside drains, sinks, and shower traps. Even though these flies are mostly harmless, they are a nuisance and predominantly indicate a clogged or poorly maintained drainage system.

No worries; there are several drain fly killers available that can get rid of these flies. But the problem is to find the right drain fly killer that actually helps. Let’s look at some of the best drain fly killer options available on the market to pick the most suitable one.

Best Drain Fly Killers That Actually Work In 2026

Most of the available drain fly killers are either chemical-based or enzyme-based. While both are effective, you need to consider your sewage type and components. For instance, a chemical-based drain fly killer might be harmful to natural bacteria inside a septic tank.

Top Biological and Enzyme-Based Drain Fly Killers

As the name implies, the biological drain fly killer uses bacteria and enzymes to break down organic buildup inside pipes. Thereby, eliminating the source of drain fly infestations altogether.

1. Dr. Pooper’s Drain Fly Killer

Accelerator’s drain fly killer gets rid of sewage flies by targeting and eliminating them from the root, where they breed. This cleaner incorporates a fast-acting foaming formula that expands deep into pipes and drains, effectively breaking down the organic buildup.

Additionally, this drain fly killer is safe for septic systems and older plumbing thanks to its enzyme-based formula. Simply put, if you got drain fly infestation, then Dr. Pooper’s Drain Fly Killer is your bestie.

2. Invade Bio Foam Conc Probiotic Drain Foam

The Invade Bio Foam is a probiotic foaming cleaner that is gentle on sewage components but harsh on drain files. Once applied, the foam expands to cover the walls of the pipes and break down the surrounding organic matter.

In addition, it targets the eggs and larvae that get stuck in the drains and completely gets rid of them as well. Thereby, ensuring there won’t be any future infestations. Trusted among users, this drain fly killer is both effective and eco-friendly.

3. Maggie’s Farm Drain & Fruit Fly Killer

The Drain & Fruit Fly Killer offered by Maggie’s Farm is a plant-based drain insecticide used to treat flies. This drain fly killer’s natural formula breaks down food waste and organic buildup effectively. And by all means, it is very safe and affordable for everyday use.

4. Kinzua Environmental FlyZyme Ultra-Strength Drain Gel

FlyZyme Ultra-Strength Drain Gel offered by Kinzua Environmental, is an enzyme-based drain insecticide. This drain fly killer uses a gel formula to dissolve organic matter that builds up in the pipe. It is a great choice for severe infestations and drains that are hard to clear.

5. Rockwell InVade Bio Drain Gel Cleaner

The InVade Bio Drain Gel Cleaner is a probiotic drain treatment made by Rockwell Labs Ltd.

Once applied, it breaks down the sludge and scum where flies breed. Thereby keeping the drains clean, which helps with long-term maintenance.

Chemical and Contact Killers

For a quicker fix, you can try using more intense chemical-based drain fly killers available on the market. But you need to be cautious not to harm household surfaces or beneficial bacteria.

6. TERRO Drain Insect Killer T590

TERRO Drain Insect Killer T590 is a chemical-based drain fly killer that gets rid of drain flies on contact. In addition, this spray helps interrupt the breeding cycle when used in combination with cleaning products.

7. Green Gobbler Fruit Fly Killer

Green Gobbler Fruit Fly Killer is a dedicated gel drain treatment that works wonders against drain flies and fruit flies. This drain fly killer’s thick gel formula clings to pipes to eliminate annoying drain fly infestations. Also, this cleaner is both affordable and widely available.

8. CLR Clear Pipes & Drains 42 Oz. Drain Opener

CLR Clear Pipes & Drains 42 Oz. is a drain cleaner and opener used to break down the buildup of soap scum, grease, and food waste that draws the flies. Note that this drain fly killer is not a dedicated fly killer; it clears organic buildup that attracts drain flies.

Tips for Best Results

Here are some useful tips for using a drain fly killer that gives effective results

  • Focus on cleaning drains, not just killing adult flies.
  • Use enzyme-based cleaners along with physical scrubbing.
  • Be consistent and repeat treatments to eliminate larvae and eggs.
  • Prioritize safety and follow the product instructions carefully.

Conclusion

Though the drain flies are small and harmless, they can be annoying at times if they are unmanaged. Lucky for you, there are several drain fly killers that can get rid of these flies. One of the best solutions is to use biological cleaners that break down organic buildup.

In addition, you can use targeted sprays for a quick fix to kill adult flies right away. On top of that, you need consistent drain maintenance to ensure your drains remain fly-free while keeping your home safe and hygienic.

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